A rat model of central venous catheter to study establishment of long-term bacterial biofilm and related acute and chronic infections.

Formation of resilient biofilms on medical devices colonized by pathogenic microorganisms is a major cause of health-care associated infection. While in vitro biofilm analyses led to promising anti-biofilm approaches, little is known about their translation to in vivo situations and on host contribu...

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Bibliographic Details
Main Authors: Ashwini Chauhan, David Lebeaux, Benoit Decante, Irene Kriegel, Marie-Christine Escande, Jean-Marc Ghigo, Christophe Beloin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3353920?pdf=render