ApoA-IMALLORCA impairs LCAT activation and induces dominant familial hypoalphalipoproteinemia

ApoA-IMALLORCA impairs LCAT activation and induces dominant familial hypoalphalipoproteinemia

Apolipoprotein (apo)A-I is the major protein component of HDL and the cofactor for LCAT. We describe a large Spanish kindred, living in the Mediterranean Island of Mallorca, that presents a dominant form of hypoalphalipoproteinemia. The lipid profile of this family was studied because the proband, a...

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Bibliographic Details
Main Authors: Jesús M. Martín-Campos, Josep Julve, Joan Carles Escolà, Jordi Ordóñez-Llanos, Joaquin Gómez, Jaume Binimelis, Francesc González-Sastre, Francisco Blanco-Vaca
Format: Article
Language:English
Published: Elsevier 2002-01-01
Series:Journal of Lipid Research
Subjects:
apolipoprotein
atherosclerosis
coronary heart disease
high density lipoprotein
molecular diagnosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520301942

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520301942

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