Regulation of Notch output dynamics via specific E(spl)-HLH factors during bristle patterning in Drosophila

The patterning of sensory bristles on the dorsal thorax of flies is regulated by two transcription factor families but the dynamics of this regulation is unclear. Here, the authors visualize seven E(spl)-HLH proteins, showing their regulated expression promotes mutual inhibition by Notch during notu...

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Bibliographic Details
Main Authors: Lydie Couturier, Khalil Mazouni, Francis Corson, François Schweisguth
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11477-2