Challenges recruiting to a proof-of-concept pharmaceutical trial for a rare disease: the trigeminal neuralgia experience

Challenges recruiting to a proof-of-concept pharmaceutical trial for a rare disease: the trigeminal neuralgia experience

Abstract Background This study aimed to describe recruitment challenges encountered during a phase IIa study of vixotrigine, a state and use-dependent Nav1.7 channel blocker, in individuals with trigeminal neuralgia. Methods This was an international, multicenter, placebo-controlled, randomized with...

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Bibliographic Details
Main Authors: Joanna M. Zakrzewska, Joanne Palmer, Lars Bendtsen, Giulia Di Stefano, Dominik A. Ettlin, Stine Maarbjerg, Mark Obermann, Valerie Morisset, Deb Steiner, Simon Tate, Giorgio Cruccu
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Trials
Subjects:
Clinical trial
Vixotrigine
Sodium channel blocker
Underrepresentation
Online Access:http://link.springer.com/article/10.1186/s13063-018-3045-1

Internet

http://link.springer.com/article/10.1186/s13063-018-3045-1

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