Specific expression of MUC21 in micropapillary elements of lung adenocarcinomas - Implications for the progression of EGFR-mutated lung adenocarcinomas.

We investigated the significance of MUC21 in EGFR-mutated lung adenocarcinoma (LADC). Two-hundred forty-one surgically resected LADCs (116 EGFR-mutated and 125 wild-type tumors) were examined for immunohistochemical expression of MUC21 protein. A polyclonal antibody and two monoclonal antibodies (he...

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Main Authors: Mai Matsumura, Koji Okudela, Yu Nakashima, Hideaki Mitsui, Kaori Denda-Nagai, Takehisa Suzuki, Hiromasa Arai, Shigeaki Umeda, Yoko Tateishi, Chihiro Koike, Toshiaki Kataoka, Tatsuro Irimura, Kenichi Ohashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215237