Effect of actinomycin D on simian rotavirus (SA11) replication in cell culture

Rotaviruses are the major cause of viral diarrhea in humans and animals. Actinomycin D (Act D) is an antibiotic that intercalates DNA and therefore inhibits DNA-dependent transcription. The current study was carried out to assess the influence of Act D on the replication of simian rotavirus (SA11) i...

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Bibliographic Details
Main Authors: C.C. Stefanelli, J.G. Castilho, M.V.J. Botelho, R.E.C. Linhares, C.M. Nozawa
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2002-04-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000400006