Gene transfection in high serum levels: case studies with new cholesterol based cationic gemini lipids.

BACKGROUND: Six new cationic gemini lipids based on cholesterol possessing different positional combinations of hydroxyethyl (-CH2CH2OH) and oligo-oxyethylene -(CH2CH2O)n- moieties were synthesized. For comparison the corresponding monomeric lipid was also prepared. Each new cationic lipid was found...

Full description

Bibliographic Details
Main Authors: Santosh K Misra, Joydeep Biswas, Paturu Kondaiah, Santanu Bhattacharya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3701654?pdf=render