Comprehensive investigation of temporal and autism-associated cell type composition-dependent and independent gene expression changes in human brains

Abstract The functions of human brains highly depend on the precise temporal regulation of gene expression, and the temporal brain transcriptome profile across lifespan has been observed. The substantial transcriptome alteration in neural disorders like autism has also been observed and is thought t...

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Bibliographic Details
Main Authors: Qianhui Yu, Zhisong He
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04356-7