Involvement of PPARγ/FSP27 in the pathogenic mechanism underlying insulin resistance: tipping the balance between lipogenesis and fat storage in adult catch-up growth rats

Involvement of PPARγ/FSP27 in the pathogenic mechanism underlying insulin resistance: tipping the balance between lipogenesis and fat storage in adult catch-up growth rats

Abstract Background Catch-up growth in adult (CUGA) is characterized by visceral fat accumulation, ectopic lipid deposition and insulin resistance (IR). Here, we investigated the determinants of these pathophysiological consequences of CUGA. Methods Rats were divided into different groups: control r...

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Bibliographic Details
Main Authors: Yan Li, Shan Yu, Lulu Chen, Xiang Hu, Juan Zheng, Xiuling Deng
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Nutrition & Metabolism
Subjects:
Catch-up growth in adult
Visceral fat accumulation
Fat storage capacity
Lipid overflow
Insulin resistance
Online Access:http://link.springer.com/article/10.1186/s12986-019-0336-9

Internet

http://link.springer.com/article/10.1186/s12986-019-0336-9

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