MiR-27a-3p/Hoxa10 Axis Regulates Angiotensin II-Induced Cardiomyocyte Hypertrophy by Targeting Kv4.3 Expression

MiR-27a-3p/Hoxa10 Axis Regulates Angiotensin II-Induced Cardiomyocyte Hypertrophy by Targeting Kv4.3 Expression

Cardiac hypertrophy is a common pathological process of various cardiovascular diseases, which is often accompanied with structural and electrical remodeling, and can even lead to sudden cardiac death. However, its molecular mechanism still remains largely unknown. Here, we induced cardiomyocyte hyp...

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Bibliographic Details
Main Authors: Xuefeng Cao, Zheng Zhang, Yu Wang, Weichao Shan, Ruiting Wang, Shufang Mao, Shi Ding, Chong Pang, Baoqun Li, Jian Zhou, Xiaoyan Guo, Na Guo, Cui Li, Jing Liang, Wenya Ma, Yu Liu, Liang Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
cardiac hypertrophy
electrical remodeling
HOXA10
miRNA-27a-3p
Ang II
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.680349/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.680349/full

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