Thermoreversible Gel-Loaded Amphotericin B for the Treatment of Dermal and Vaginal Candidiasis

Thermoreversible Gel-Loaded Amphotericin B for the Treatment of Dermal and Vaginal Candidiasis

The present study was designed to develop a thermoreversible gel of Pluronic (P407) loaded amphotericin B (AmB-gel) for the dermal and vaginal treatment of candidiasis. P407 was used as a copolymer to exploit potential advantages related to increasing drug concentration in the tissue layer in order...

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Bibliographic Details
Main Authors: Lilian Sosa, Ana Cristina Calpena, Marcelle Silva-Abreu, Lupe Carolina Espinoza, María Rincón, Nuria Bozal, Oscar Domenech, María José Rodríguez-Lagunas, Beatriz Clares
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Pharmaceutics
Subjects:
thermoreversible gel
poloxamer 407
candidiasis
amphotericin B
skin and vaginal mucosa
Online Access:https://www.mdpi.com/1999-4923/11/7/312

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https://www.mdpi.com/1999-4923/11/7/312

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