Single-cell RNA-Seq analysis reveals dynamic trajectories during mouse liver development

Single-cell RNA-Seq analysis reveals dynamic trajectories during mouse liver development

Abstract Background The differentiation and maturation trajectories of fetal liver stem/progenitor cells (LSPCs) are not fully understood at single-cell resolution, and a priori knowledge of limited biomarkers could restrict trajectory tracking. Results We employed marker-free single-cell RNA-Seq to...

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Bibliographic Details
Main Authors: Xianbin Su, Yi Shi, Xin Zou, Zhao-Ning Lu, Gangcai Xie, Jean Y. H. Yang, Chong-Chao Wu, Xiao-Fang Cui, Kun-Yan He, Qing Luo, Yu-Lan Qu, Na Wang, Lan Wang, Ze-Guang Han
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Genomics
Subjects:
Liver stem/progenitor cells
Single-cell RNA-Seq
Developmental trajectory
Cholangiocyte
Fate decision
Online Access:http://link.springer.com/article/10.1186/s12864-017-4342-x

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http://link.springer.com/article/10.1186/s12864-017-4342-x

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