Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization

Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization

A 5.3 Å resolution, cryo-electron microscopy (cryoEM) map of Chikungunya virus-like particles (VLPs) has been interpreted using the previously published crystal structure of the Chikungunya E1-E2 glycoprotein heterodimer. The heterodimer structure was divided into domains to obtain a good fit to the...

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Bibliographic Details
Main Authors: Siyang Sun, Ye Xiang, Wataru Akahata, Heather Holdaway, Pankaj Pal, Xinzheng Zhang, Michael S Diamond, Gary J Nabel, Michael G Rossmann
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-04-01
Series:eLife
Subjects:
neutralizing antibody
Chikungunya virus
electron microscopy
pseudo-atomic
structure
envelope protein
Online Access:https://elifesciences.org/articles/00435

Internet

https://elifesciences.org/articles/00435

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