The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 years

The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 years

<p>Abstract</p> <p>Background</p> <p>The occurrence of asthma is weakly explained by known genetic variants. Epigenetic marks, DNA methylation (DNA-M) in particular, are considered to add to the explanation of asthma. However, no etiological model has yet been developed...

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Bibliographic Details
Main Authors: Soto-Ramírez Nelís, Arshad Syed Hasan, Holloway John W, Zhang Hongmei, Schauberger Eric, Ewart Susan, Patil Veeresh, Karmaus Wilfried
Format: Article
Language:English
Published: BMC 2013-01-01
Series:Clinical Epigenetics
Subjects:
Interleukin-4 receptor gene
DNA methylation
Genetic variants
Asthma
Epigenetics
Online Access:http://www.clinicalepigeneticsjournal.com/content/5/1/1

Internet

http://www.clinicalepigeneticsjournal.com/content/5/1/1

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