Phytochemicals from Ruta graveolens Activate TAS2R Bitter Taste Receptors and TRP Channels Involved in Gustation and Nociception

Phytochemicals from Ruta graveolens Activate TAS2R Bitter Taste Receptors and TRP Channels Involved in Gustation and Nociception

Ruta graveolens (rue) is a spontaneous plant in the Mediterranean area with a strong aroma and a very intense bitter taste, used in gastronomy and in folk medicine. From the leaves, stems and fruits of rue, we isolated rutin, rutamarin, three furanocoumarins, two quinolinic alkaloids, a dicoumarin a...

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Bibliographic Details
Main Authors: Giuseppe Mancuso, Gigliola Borgonovo, Leonardo Scaglioni, Angela Bassoli
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Molecules
Subjects:
Ruta graveolens
bitter taste
TAS2Rs receptors
chemesthesis
TRP channels
Online Access:http://www.mdpi.com/1420-3049/20/10/18907

Internet

http://www.mdpi.com/1420-3049/20/10/18907

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