Unconventional Pro-inflammatory CD4+ T Cell Response in B Cell-Deficient Mice Infected with Trypanosoma cruzi

Unconventional Pro-inflammatory CD4+ T Cell Response in B Cell-Deficient Mice Infected with Trypanosoma cruzi

Chagas disease, caused by the parasite Trypanosoma cruzi, is endemic in Latin America but has become a global public health concern by migration of infected people. It has been reported that parasite persistence as well as the intensity of the inflammatory immune response are determinants of the cli...

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Bibliographic Details
Main Authors: Melisa Gorosito Serrán, Jimena Tosello Boari, Facundo Fiocca Vernengo, Cristian G. Beccaría, María C. Ramello, Daniela A. Bermejo, Amelia G. Cook, Carola G. Vinuesa, Carolina L. Montes, Eva V. Acosta Rodriguez, Adriana Gruppi
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Immunology
Subjects:
Trypanosoma cruzi
Chagas disease
B cell
CD4+ T cells
inflammation
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01548/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01548/full

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