Nucleic acid delivery to mesenchymal stem cells: a review of nonviral methods and applications

Abstract Background Mesenchymal stem cells (MSCs) are multipotent stem cells that can be isolated and expanded from many tissues, and are being investigated for use in cell therapies. Though MSC therapies have demonstrated some success, none have been FDA approved for clinical use. MSCs lose stemnes...

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Bibliographic Details
Main Authors: Andrew Hamann, Albert Nguyen, Angela K. Pannier
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Journal of Biological Engineering
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13036-019-0140-0