GC-rich sequence elements recruit PRC2 in mammalian ES cells.

GC-rich sequence elements recruit PRC2 in mammalian ES cells.

Polycomb proteins are epigenetic regulators that localize to developmental loci in the early embryo where they mediate lineage-specific gene repression. In Drosophila, these repressors are recruited to sequence elements by DNA binding proteins associated with Polycomb repressive complex 2 (PRC2). Ho...

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Bibliographic Details
Main Authors: Eric M Mendenhall, Richard P Koche, Thanh Truong, Vicky W Zhou, Biju Issac, Andrew S Chi, Manching Ku, Bradley E Bernstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3000368?pdf=render

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http://europepmc.org/articles/PMC3000368?pdf=render

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