Integrative Analysis Extracts a Core ceRNA Network of the Fetal Hippocampus With Down Syndrome

Integrative Analysis Extracts a Core ceRNA Network of the Fetal Hippocampus With Down Syndrome

Accumulating evidence suggests that circular RNAs (circRNAs)—miRNA–mRNA ceRNA regulatory network—may play an important role in neurological disorders, such as Alzheimer’s disease (AD). Interestingly, neuropathological changes that closely resemble AD have been found in nearly all Down syndrome (DS)...

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Bibliographic Details
Main Authors: Shengran Wang, Xia Tang, Litao Qin, Weili Shi, Shasha Bian, Zhaokun Wang, Qingqing Wang, Xin Wang, Jianqin Gu, Bingtao Hao, Keyue Ding, Shixiu Liao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Genetics
Subjects:
Down syndrome (DS)
hippocampus
competing endogenous RNAs (ceRNAs)
single-cell RNA sequencing
epigenetic
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.565955/full

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https://www.frontiersin.org/articles/10.3389/fgene.2020.565955/full

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