The analysis of glutamate and glutamine frequencies in human proteins as marker of tissue oxygenation

In this study, we investigated whether the relative abundance of glutamate and glutamine in human proteins reflects the availability of these amino acids (AAs) dictated by the cellular context. In particular, because hypoxia increases the conversion of glutamate to glutamine, we hypothesized that th...

Full description

Bibliographic Details
Main Authors: Annamaria Vernone, Chiara Ricca, Daniela Merlo, Gianpiero Pescarmona, Francesca Silvagno
Format: Article
Language:English
Published: The Royal Society 2019-04-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.181891