The analysis of glutamate and glutamine frequencies in human proteins as marker of tissue oxygenation
In this study, we investigated whether the relative abundance of glutamate and glutamine in human proteins reflects the availability of these amino acids (AAs) dictated by the cellular context. In particular, because hypoxia increases the conversion of glutamate to glutamine, we hypothesized that th...
Main Authors: | Annamaria Vernone, Chiara Ricca, Daniela Merlo, Gianpiero Pescarmona, Francesca Silvagno |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2019-04-01
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Series: | Royal Society Open Science |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.181891 |
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