Molecular Determinants of the Kinetic Binding Properties of Antihistamines at the Histamine H<sub>1</sub> Receptors

The binding affinity of ligands for their receptors is determined by their kinetic and thermodynamic binding properties. Kinetic analyses of the rate constants of association and dissociation (<i>k</i><sub>on</sub> and <i>k</i><sub>off</sub>, respectiv...

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Bibliographic Details
Main Authors: Hayato Akimoto, Yoshihiro Uesawa, Shigeru Hishinuma
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/5/2400