Effect of Gliadin on Permeability of Intestinal Biopsy Explants from Celiac Disease Patients and Patients with Non-Celiac Gluten Sensitivity

Effect of Gliadin on Permeability of Intestinal Biopsy Explants from Celiac Disease Patients and Patients with Non-Celiac Gluten Sensitivity

Background: Intestinal exposure to gliadin leads to zonulin upregulation and consequent disassembly of intercellular tight junctions and increased intestinal permeability. We aimed to study response to gliadin exposure, in terms of barrier function and cytokine secretion, using intestinal biopsies o...

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Bibliographic Details
Main Authors: Justin Hollon, Elaine Leonard Puppa, Bruce Greenwald, Eric Goldberg, Anthony Guerrerio, Alessio Fasano
Format: Article
Language:English
Published: MDPI AG 2015-02-01
Series:Nutrients
Subjects:
celiac disease
gluten sensitivity
IL-10
Online Access:http://www.mdpi.com/2072-6643/7/3/1565

Internet

http://www.mdpi.com/2072-6643/7/3/1565

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