The function of cortactin in the clustering of acetylcholine receptors at the vertebrate neuromuscular junction.

BACKGROUND:Postsynaptic enrichment of acetylcholine receptors (AChRs) at the vertebrate neuromuscular junction (NMJ) depends on the activation of the muscle receptor tyrosine MuSK by neural agrin. Agrin-stimulation of MuSK is known to initiate an intracellular signaling cascade that leads to the clu...

Full description

Bibliographic Details
Main Authors: Raghavan Madhavan, Zhuolin L Gong, Jin Jin Ma, Ariel W S Chan, H Benjamin Peng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2793544?pdf=render