Complex of EGCG with Cu(II) Suppresses Amyloid Aggregation and Cu(II)-Induced Cytotoxicity of α-Synuclein

Complex of EGCG with Cu(II) Suppresses Amyloid Aggregation and Cu(II)-Induced Cytotoxicity of α-Synuclein

Accumulation of α-synuclein (α-Syn) is a remarkable pathology for Parkinson’s disease (PD), therefore clearing it is possibly a promising strategy for treating PD. Aberrant copper (Cu(II)) homeostasis and oxidative stress play critical roles in the abnormal aggregation of...

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Bibliographic Details
Main Authors: Yilong Teng, Juan Zhao, Lulu Ding, Yu Ding, Ping Zhou
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Molecules
Subjects:
Parkinson’s disease
α-synuclein
copper
EGCG
complex
Online Access:https://www.mdpi.com/1420-3049/24/16/2940

Internet

https://www.mdpi.com/1420-3049/24/16/2940

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