A computational pipeline for high- throughput discovery of cis-regulatory noncoding RNA in prokaryotes.

Noncoding RNAs (ncRNAs) are important functional RNAs that do not code for proteins. We present a highly efficient computational pipeline for discovering cis-regulatory ncRNA motifs de novo. The pipeline differs from previous methods in that it is structure-oriented, does not require a multiple-sequ...

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Bibliographic Details
Main Authors: Zizhen Yao, Jeffrey Barrick, Zasha Weinberg, Shane Neph, Ronald Breaker, Martin Tompa, Walter L Ruzzo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-07-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1913097?pdf=render