Curcumin-Mediated Apoptotic Cell Death in Papillary Thyroid Cancer and Cancer Stem-Like Cells through Targeting of the JAK/STAT3 Signaling Pathway

Curcumin-Mediated Apoptotic Cell Death in Papillary Thyroid Cancer and Cancer Stem-Like Cells through Targeting of the JAK/STAT3 Signaling Pathway

The constitutive activation of Janus Kinase/Signal Transducer and Activator of Transcription (JAK/STAT) signal transduction is well elucidated in STAT3-mediated oncogenesis related to thyroid cancer and is considered to be a plausible therapeutic target. Hence, we investigated whether curcumin, a na...

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Bibliographic Details
Main Authors: Abdul Q. Khan, Eiman I. Ahmed, Noor Elareer, Hamna Fathima, Kirti S. Prabhu, Kodappully S. Siveen, Michal Kulinski, Fouad Azizi, Said Dermime, Aamir Ahmad, Martin Steinhoff, Shahab Uddin
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:International Journal of Molecular Sciences
Subjects:
thyroid cancer
curcumin
cisplatin
stat3
cell proliferation
cancer stem cells
apoptosis
Online Access:https://www.mdpi.com/1422-0067/21/2/438

Internet

https://www.mdpi.com/1422-0067/21/2/438

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