S100B Impairs Oligodendrogenesis and Myelin Repair Following Demyelination Through RAGE Engagement

Increased expression of S100B and its specific receptor for advanced glycation end products (RAGE) has been described in patients with multiple sclerosis (MS), being associated with an active demyelinating process. We previously showed that a direct neutralization of S100B reduces lysophosphatidylch...

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Bibliographic Details
Main Authors: Gisela Santos, Andreia Barateiro, Dora Brites, Adelaide Fernandes
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00279/full