A Novel Approach on Drug Delivery: Investigation of A New Nano-Formulation of Liposomal Doxorubicin and Biological Evaluation of Entrapped Doxorubicin on Various Osteosarcoma Cell Lines

Objective In this study we prepared a novel formulation of liposomal doxorubicin (L- DOX). The drug dose was optimized by analyses of cellular uptake and cell viability of osteosarcoma (OS) cell lines upon exposure to nanoliposomes that contained varying DOX concentrations. We intended to reduce th...

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Bibliographic Details
Main Authors: Fateme Haghiralsadat, Ghasem Amoabediny, Mohammad Hasan Sheikhha, Tymour Forouzanfar, Javad Mohammadnejad, Behrouz Zandieh-doulabi
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2017-05-01
Series:Cell Journal
Subjects:
Online Access:http://celljournal.org/journal/article/12049/download