A recombinant multi-antigen vaccine formulation containing Babesia bovis merozoite surface antigens MSA-2a1, MSA-2b and MSA-2c elicits invasion-inhibitory antibodies and IFN-γ producing cells

Abstract Background Babesia bovis is a tick-transmitted protozoan hemoparasite and the causative agent of bovine babesiosis, a potential risk to more than 500 million cattle worldwide. The vaccines currently available are based on attenuated parasites, which are difficult to produce, and are only re...

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Bibliographic Details
Main Authors: Alba Marina Gimenez, Katia S. Françoso, Jonatan Ersching, Marcelo Y. Icimoto, Vitor Oliveira, Anabel E. Rodriguez, Leonhard Schnittger, Monica Florin-Christensen, Mauricio M. Rodrigues, Irene S. Soares
Format: Article
Language:English
Published: BMC 2016-11-01
Series:Parasites & Vectors
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13071-016-1862-1