A recombinant multi-antigen vaccine formulation containing Babesia bovis merozoite surface antigens MSA-2a1, MSA-2b and MSA-2c elicits invasion-inhibitory antibodies and IFN-γ producing cells
Abstract Background Babesia bovis is a tick-transmitted protozoan hemoparasite and the causative agent of bovine babesiosis, a potential risk to more than 500 million cattle worldwide. The vaccines currently available are based on attenuated parasites, which are difficult to produce, and are only re...
Main Authors: | Alba Marina Gimenez, Katia S. Françoso, Jonatan Ersching, Marcelo Y. Icimoto, Vitor Oliveira, Anabel E. Rodriguez, Leonhard Schnittger, Monica Florin-Christensen, Mauricio M. Rodrigues, Irene S. Soares |
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Format: | Article |
Language: | English |
Published: |
BMC
2016-11-01
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Series: | Parasites & Vectors |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13071-016-1862-1 |
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