Ras-Induced miR-146a and 193a Target Jmjd6 to Regulate Melanoma Progression

Ras-Induced miR-146a and 193a Target Jmjd6 to Regulate Melanoma Progression

Ras genes are among the most commonly mutated genes in human cancer; yet our understanding of their oncogenic activity at the molecular mechanistic level is incomplete. To identify downstream events that mediate ras-induced cellular transformation in vivo, we analyzed global microRNA expression in t...

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Bibliographic Details
Main Authors: Viviana Anelli, Anita Ordas, Susanne Kneitz, Leonel Munoz Sagredo, Victor Gourain, Manfred Schartl, Annemarie H. Meijer, Marina Mione
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Genetics
Subjects:
zebrafish
cancer models
microRNA
Jmjd6
ras
melanoma
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00675/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00675/full

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