Intraoperative Use of Remifentanil and Opioid Induced Hyperalgesia/Acute Opioid Tolerance - Systematic review

IntroductionThe use of opioids has been increasing in operating room and intensive care unit to provide perioperative analgesia as well as stable hemodynamics. However, many authors have suggested that the use of opioids is associated with the expression of acute opioid tolerance (AOT) and opioid-in...

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Bibliographic Details
Main Authors: Sang Hun eKim, Nicoleta eStoicea, Suren eSoghomonyan, Sergio Daniel Bergese
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00108/full