Multiple docking analysis and In silico absorption, distribution, metabolism, excretion, and toxicity screening of anti-leprosy phytochemicals and dapsone against dihydropteroate synthase of Mycobacterium leprae

Background: Leprosy is a neglected tropical disease affecting millions of people. The current treatment against leprosy includes various antibacterial drugs of which dapsone is known to bind to dihydropteroate synthase of Mycobacterium leprae. Dapsone is an expensive antibacterial drug with many sid...

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Bibliographic Details
Main Authors: Sumit T Halder, Tehseen M Dhorajiwala, Lalit R Samant
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:International Journal of Mycobacteriology
Subjects:
Online Access:http://www.ijmyco.org/article.asp?issn=2212-5531;year=2019;volume=8;issue=3;spage=229;epage=236;aulast=Halder