Calcium Ionophore-Induced Extracellular Vesicles Mediate Cytoprotection against Simulated Ischemia/Reperfusion Injury in Cardiomyocyte-Derived Cell Lines by Inducing Heme Oxygenase 1

Calcium Ionophore-Induced Extracellular Vesicles Mediate Cytoprotection against Simulated Ischemia/Reperfusion Injury in Cardiomyocyte-Derived Cell Lines by Inducing Heme Oxygenase 1

Cardioprotection against ischemia/reperfusion injury is still an unmet clinical need. The transient activation of Toll-like receptors (TLRs) has been implicated in cardioprotection, which may be achieved by treatment with blood-derived extracellular vesicles (EVs). However, since the isolation of EV...

Full description

Bibliographic Details
Main Authors: Peter Pečan, Szabolcs Hambalkó, Van Thai Ha, Csilla T. Nagy, Csilla Pelyhe, Duško Lainšček, Bence Kenyeres, Gábor B. Brenner, Anikó Görbe, Ágnes Kittel, Monika Barteková, Péter Ferdinandy, Mateja Manček-Keber, Zoltán Giricz
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
extracellular vesicles
TLR4
HO-1
cardioprotection
ischemia/reperfusion injury
Online Access:https://www.mdpi.com/1422-0067/21/20/7687

Internet

https://www.mdpi.com/1422-0067/21/20/7687

Similar Items