Genetic mapping of fitness determinants across the malaria parasite Plasmodium falciparum life cycle.

Determining the genetic basis of fitness is central to understanding evolution and transmission of microbial pathogens. In human malaria parasites (Plasmodium falciparum), most experimental work on fitness has focused on asexual blood stage parasites, because this stage can be easily cultured, altho...

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Bibliographic Details
Main Authors: Xue Li, Sudhir Kumar, Marina McDew-White, Meseret Haile, Ian H Cheeseman, Scott Emrich, Katie Button-Simons, François Nosten, Stefan H I Kappe, Michael T Ferdig, Tim J C Anderson, Ashley M Vaughan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-10-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008453