Synthesis and antimicrobial evaluation of some 1-(4-arylthiazol-2-yl)-1′-(aryl/heteroaryl)-3,3′-dimethyl-[4,5′-bi-1H-pyrazol]-5-ols

Synthesis and antimicrobial evaluation of some 1-(4-arylthiazol-2-yl)-1′-(aryl/heteroaryl)-3,3′-dimethyl-[4,5′-bi-1H-pyrazol]-5-ols

A series of sixteen 1-(4-arylthiazol-2-yl)-1′-(aryl/heteroaryl)-3,3′-dimethyl-[ 4,5′-bi-1H-pyrazol]-5-ols (7a–p) was synthesized starting from dehydroacetic acid (DHA, 1) via the stepwise formation of thiosemicarbazone (2), 3-(1-(2-(4-arylthiazol-2-yl)hydrazono)ethyl)-4-hydroxy-6-methyl-2H-pyran- -2...

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Bibliographic Details
Main Authors: Mor Satbir, Mohil Rajni, Nagoria Savita, Kumar Ashwani
Format: Article
Language:English
Published: Serbian Chemical Society 2017-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
bipyrazoles
antibacterial
antifungal
docking simulations
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2017/0352-51391700002M.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0352-5139/2017/0352-51391700002M.pdf

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