Using regulatory genomics data to interpret the function of disease variants and prioritise genes from expression studies [version 2; referees: 2 approved]

The identification of therapeutic targets is a critical step in the research and developement of new drugs, with several drug discovery programmes failing because of a weak linkage between target and disease. Genome-wide association studies and large-scale gene expression experiments are providing i...

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Bibliographic Details
Main Author: Enrico Ferrero
Format: Article
Language:English
Published: F1000 Research Ltd 2018-02-01
Series:F1000Research
Online Access:https://f1000research.com/articles/7-121/v2