Temporal and spatial regulation of protein cross-linking by the pre-assembled substrates of a Bacillus subtilis spore coat transglutaminase.

In many cases protein assemblies are stabilized by covalent bonds, one example of which is the formation of intra- or intermolecular ε-(γ-glutamyl)lysil cross-links catalyzed by transglutaminases (TGases). Because of the potential for unwanted cross-linking reactions, the activities of many TGases h...

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Bibliographic Details
Main Authors: Catarina G Fernandes, Diogo Martins, Guillem Hernandez, Ana L Sousa, Carolina Freitas, Erin M Tranfield, Tiago N Cordeiro, Mónica Serrano, Charles P Moran, Adriano O Henriques
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-04-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1007912