Cyst growth, polycystins, and primary cilia in autosomal dominant polycystic kidney disease
The primary cilium of renal epithelia acts as a transducer of extracellular stimuli. Polycystin (PC)1 is the protein encoded by the PKD1 gene that is responsible for the most common and severe form of autosomal dominant polycystic kidney disease (ADPKD). PC1 forms a complex with PC2 via their respec...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
The Korean Society of Nephrology
2014-06-01
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| Series: | Kidney Research and Clinical Practice |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211913214000333 |