Non-replication of genome-wide based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes.

The INSIG2 rs7566605 and PFKP rs6602024 polymorphisms have been identified as obesity gene variants in genome-wide association (GWA) studies. However, replication has been contradictory for both variants. The aims of this study were to validate these obesity-associations through case-control studies...

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Main Authors: Camilla H Andreasen, Mette S Mogensen, Knut Borch-Johnsen, Annelli Sandbaek, Torsten Lauritzen, Thorkild I A Sørensen, Lars Hansen, Katrine Almind, Torben Jørgensen, Oluf Pedersen, Torben Hansen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2483934?pdf=render