Metallochaperones regulate intracellular copper levels.

Metallochaperones regulate intracellular copper levels.

Copper (Cu) is an important enzyme co-factor that is also extremely toxic at high intracellular concentrations, making active efflux mechanisms essential for preventing Cu accumulation. Here, we have investigated the mechanistic role of metallochaperones in regulating Cu efflux. We have constructed...

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Bibliographic Details
Main Authors: W Lee Pang, Amardeep Kaur, Alexander V Ratushny, Aleksandar Cvetkovic, Sunil Kumar, Min Pan, Adam P Arkin, John D Aitchison, Michael W W Adams, Nitin S Baliga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3551603?pdf=render

Internet

http://europepmc.org/articles/PMC3551603?pdf=render

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