Molecular characterization of mesenchymal stem cells in human osteoarthritis cartilage reveals contribution to the OA phenotype

Abstract Adult human articular cartilage harbors a population of CD166+ mesenchymal stem cell-like progenitors that become more numerous during osteoarthritis (OA). While their role is not well understood, here we report that they are indeed part of cellular clusters formed in OA cartilage, which is...

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Bibliographic Details
Main Authors: Chathuraka T. Jayasuriya, Nan Hu, Jing Li, Nicholas Lemme, Richard Terek, Michael G. Ehrlich, Qian Chen
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25395-8