Chlorinated Water Modulates the Development of Colorectal Tumors with Chromosomal Instability and Gut Microbiota in Apc-Deficient Mice.

The gastrointestinal tract is continuously exposed to a variety of chemicals and commensal bacteria. Recent studies have shown that changes in gut microbial populations caused by chlorine or other chemicals in the drinking water influence the development of human colorectal cancer, although the mech...

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Bibliographic Details
Main Authors: Tatsunari Sasada, Takao Hinoi, Yasufumi Saito, Tomohiro Adachi, Yuji Takakura, Yasuo Kawaguchi, Yusuke Sotomaru, Kazuhiro Sentani, Naohide Oue, Wataru Yasui, Hideki Ohdan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0132435