Functional characterization of cytochrome P450-derived epoxyeicosatrienoic acids in adipogenesis and obesity

Functional characterization of cytochrome P450-derived epoxyeicosatrienoic acids in adipogenesis and obesity

Adipogenesis plays a critical role in the initiation and progression of obesity. Although cytochrome P450 (CYP)-derived epoxyeicosatrienoic acids (EETs) have emerged as a potential therapeutic target for cardiometabolic disease, the functional contribution of EETs to adipogenesis and the pathogenesi...

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Bibliographic Details
Main Authors: Weibin Zha, Matthew L. Edin, Kimberly C. Vendrov, Robert N. Schuck, Fred B. Lih, Jawahar Lal Jat, J. Alyce Bradbury, Laura M. DeGraff, Kunjie Hua, Kenneth B. Tomer, John R. Falck, Darryl C. Zeldin, Craig R. Lee
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Journal of Lipid Research
Subjects:
adipose tissue
arachidonic acid
eicosanoids
high-fat diet
metabolomics
soluble epoxide hydrolase
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520350161

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http://www.sciencedirect.com/science/article/pii/S0022227520350161

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