QT PRODACT: Sensitivity and Specificity of the Canine Telemetry Assay for Detecting Drug-Induced QT Interval Prolongation

The purpose of this investigation was to define the sensitivity and specificity of the canine telemetry assay for detecting drug-induced QT interval prolongation. Data from twelve studies generated in the QT PRODACT project were used in this investigation. The study design was a 4 × 4 Latin square c...

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Bibliographic Details
Main Authors: Hiroyasu Miyazaki, Hiroyuki Watanabe, Tetsuya Kitayama, Masahiro Nishida, Yasuhiro Nishi, Koji Sekiya, Hideki Suganami, Keiji Yamamoto
Format: Article
Language:English
Published: Elsevier 2005-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319320584