Fibroblast growth factor 2 supports osteoblastic niche cells during hematopoietic homeostasis recovery after bone marrow suppression

Fibroblast growth factor 2 supports osteoblastic niche cells during hematopoietic homeostasis recovery after bone marrow suppression

Abstract Background Hematopoietic stem cell (HSC) maintenance requires a specific microenvironment. HSC niches can be activated by tissue damaging chemotherapeutic drugs and various cell signaling molecules such as SDF-1 and FGF, which might also result in bone marrow stress. Recent research has ins...

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Bibliographic Details
Main Authors: Kyung-Ae Yoon, YeonSung Son, Young-Jin Choi, Joo-Hyun Kim, Je-Yoel Cho
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Cell Communication and Signaling
Subjects:
FGF2
Hematopoietic stem cell
Niche
Osteoblast
Osteoprogenitor
Online Access:http://link.springer.com/article/10.1186/s12964-017-0181-2

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http://link.springer.com/article/10.1186/s12964-017-0181-2

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