Self-adjuvanting C18 lipid vinil sulfone-PP2A vaccine: study of the induced immunomodulation against Trichuris muris infection

Self-adjuvanting C18 lipid vinil sulfone-PP2A vaccine: study of the induced immunomodulation against Trichuris muris infection

Despite the importance of the adjuvant in the immunization process, very few adjuvants merge with the antigens in vaccines. A synthetic self-adjuvant oleic-vinyl sulfone (OVS) linked to the catalytic region of recombinant serine/threonine phosphatase 2A from the nematode Angiostrongylus costaricensi...

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Bibliographic Details
Main Authors: M. Gomez-Samblas, J. J. García-Rodríguez, M. Trelis, D. Bernal, F. J. Lopez-Jaramillo, F. Santoyo-Gonzalez, S. Vilchez, A. M. Espino, F. Bolás-Fernández, A. Osuna
Format: Article
Language:English
Published: The Royal Society 2017-01-01
Series:Open Biology
Subjects:
trichuris muris vaccination
self-assembling lipopeptide rpp2a
chemokines
cytokines
lipid vinyl sulfone
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.170031

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https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.170031

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