Differential Growth Inhibitory Effects of Highly Oxygenated Guaianolides Isolated from the Middle Eastern Indigenous Plant Achillea falcata in HCT-116 Colorectal Cancer Cells

Differential Growth Inhibitory Effects of Highly Oxygenated Guaianolides Isolated from the Middle Eastern Indigenous Plant Achillea falcata in HCT-116 Colorectal Cancer Cells

Medicinal plants play a crucial role in traditional medicine and in the maintenance of human health worldwide. Sesquiterpene lactones represent an interesting group of plant-derived compounds that are currently being tested as lead drugs in cancer clinical trials. Achillea falcata is a medicinal pla...

Full description

Bibliographic Details
Main Authors: Nadine Darwiche, Najat A. Saliba, Lamis Al Aaraj, Tarek Ghaddar, Hala Gali-Muhtasib, Rita Tohme
Format: Article
Language:English
Published: MDPI AG 2013-07-01
Series:Molecules
Subjects:
Achillea falcata
sesquiterpene lactones
guaianolides
colorectal cancer cells
bioassay-guided fractionation
structure-activity relationship
Online Access:http://www.mdpi.com/1420-3049/18/7/8275

Internet

http://www.mdpi.com/1420-3049/18/7/8275

Similar Items