Role of pyruvate kinase M20-regulated glycolysis in inflammatory activation of macrophages in diabetic nephropathy

Role of pyruvate kinase M20-regulated glycolysis in inflammatory activation of macrophages in diabetic nephropathy

Objective To explore the role of pyruvate kinase M20 (PKM2)-regulated glycolysis on nod-like receptor protein 3 (NLRP3)- and absentin melanoma 2 (AIM2)-mediated inflammatory activation of macrophages in diabetic nephropathy (DN). Methods Renal biopsy samples from 30 DN patients and tumor-adjacent re...

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Bibliographic Details
Main Authors: XIE Shan, XU Xingxin
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2020-12-01
Series:Di-san junyi daxue xuebao
Subjects:
diabetic nephropathy
macrophages
glycolysis
pyruvate kinase m2
inflammasome
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202007015.htm

Internet

http://aammt.tmmu.edu.cn/Upload/rhtml/202007015.htm

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